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Supramolecular Architectures Self‐assembled from Asymmetrical Hetero Cyclopeptides
Author(s) -
Qin SiYong,
Xu XiaoDing,
Chen ChangSheng,
Chen JingXiao,
Li ZeYong,
Zhuo RenXi,
Zhang XianZheng
Publication year - 2011
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201100052
Subject(s) - supramolecular chemistry , nanotechnology , materials science , self assembly , polymer science , chemistry , molecule , organic chemistry
In this study, two asymmetrical cyclopeptides (CP1 and CP2) were designed and synthesized. The self‐assembly behaviors of the asymmetrical cyclopeptides at varying pHs were investigated in terms of transmission electron microscopy (TEM), circular dichroism (CD), and Fourier transform infrared (FT‐IR) spectroscopy. It was found that the self‐assembly of CP1 resulted in the formation of nanofibers with α‐helix conformation, while CP2 self‐assembled into well‐ordered nanorods with anti‐parallel β‐sheet conformation. The strategy demonstrated here presents great potential for preparation of well‐defined nanostructures via rationally designing the molecular structures of cyclopeptides.