Premium
Macromol. Rapid Commun. 12/2010
Author(s) -
Zhu Qing,
Zhan Ruoyu,
Liu Bin
Publication year - 2010
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201090030
Subject(s) - polymer , conjugated system , homogeneous , cover (algebra) , trypsin , förster resonance energy transfer , nanotechnology , fluorescence , energy transfer , combinatorial chemistry , materials science , chemistry , polymer science , organic chemistry , physics , optics , chemical physics , engineering , mechanical engineering , thermodynamics , enzyme
Back Cover: The image presents a novel and simple conjugated polymer–fluorescent probe based platform for trypsin detection from protein mixtures in homogeneous solution. This platform takes advantage of specific interaction between the probe and the active site of trypsin and the electrostatic interaction between the polymer and the protein to mediate energy transfer between the polymer and the probe. This method does not require any separation steps, which should facilitate high‐throughput protease screening and drug discovery. Further details can be found in the article by Q. Zhu, R. Zhan, and B. Liu * on page 1060 .