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Precision Polymers—Modern Tools to Understand and Program Macromolecular Interactions
Author(s) -
Börner Hans G.
Publication year - 2011
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201000646
Subject(s) - macromolecule , polymer , monomer , copolymer , dispersity , sequence (biology) , materials science , nanotechnology , block (permutation group theory) , chemistry , polymer science , polymer chemistry , organic chemistry , mathematics , biochemistry , geometry
AB‐block copolymers composed of a common synthetic polymer part and a monodisperse, monomer sequence‐defined segment are considered belonging to the class of “Precision Polymers.” This overview summarizes the possibilities that arise from those precisely adjustable, functional polymers for materials science applications. The freely programmable monomer sequence of the discrete peptide segment allows adjusting properties such as interaction capabilities. This can be exploited to (i) specifically solubilize and transport low molecular weight drugs, (ii) to pack DNA, (iii) to direct crystallization, or (iv) to modulate adhesion behavior of cells on material surfaces. As evident from proteins, the room to improve the precision of synthetic macromolecules will offer plenty of opportunities.