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Cross‐Linked Multilayers of Poly(vinyl amine) as a Single Component and Their Interaction with Proteins
Author(s) -
Dragan Ecaterina S.,
Bucatariu Florin
Publication year - 2010
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200900630
Subject(s) - component (thermodynamics) , amine gas treating , polymer chemistry , materials science , chemistry , chemical engineering , polymer science , organic chemistry , physics , thermodynamics , engineering
Abstract Novel multilayer thin films that consist solely of cross‐linked single component layers are generated by a selective cross‐linking of the poly(vinyl amine) (PVAm) layers in [PVAm/poly(acrylic acid) (PAA)] n thin films constructed either on silica particles or silicon wafers, followed by the removal of PAA. The surface topography of the (PVAm) n multilayer thin films, before and after the adsorption of human serum albumin (HSA), has been studied by atomic force microscopy on the freeze‐dried films. The decrease of the average roughness of the film after the adsorption of HSA showed the protein was adsorbed into the (PVAm) n film making these films potential reservoirs for proteins.