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Gold Nanoparticles Functionalized by a Dextran‐Based pH‐ and Temperature‐Sensitive Polymer
Author(s) -
Lv Weipeng,
Liu Shuoqi,
Fan Xiaobin,
Wang Shulan,
Zhang Guoliang,
Zhang Fengbao
Publication year - 2010
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200900624
Subject(s) - dextran , polymer , nanoparticle , polymerization , chemical engineering , materials science , colloidal gold , polymer chemistry , raft , chain transfer , reversible addition−fragmentation chain transfer polymerization , chemistry , nanotechnology , radical polymerization , chromatography , composite material , engineering
A dextran‐based dual‐sensitive polymer is employed to endow gold nanoparticles with stability and pH‐ and temperature‐sensitivity. The dual‐sensitive polymer is prepared by RAFT polymerization of N ‐isopropylacrylamide from trithiocarbonate groups linked to dextran and succinoylation of dextran after polymerization. The functionalized nanoparticles show excellent stability under various conditions and can be stored in powder‐form. UV and DLS measurements confirm that the temperature‐induced optical changes and aggregation behaviors of the particles are strongly dependent on pH.