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Droplet Microfluidics for Fabrication of Non‐Spherical Particles
Author(s) -
Shum Ho Cheung,
Abate Adam R.,
Lee Daeyeon,
Studart André R.,
Wang Baoguo,
Chen ChiaHung,
Thiele Julian,
Shah Rhutesh K.,
Krummel Amber,
Weitz David A.
Publication year - 2010
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200900590
Subject(s) - microfluidics , dispersity , coalescence (physics) , nanotechnology , fabrication , materials science , flow focusing , polymer , polymer chemistry , physics , composite material , medicine , alternative medicine , pathology , astrobiology
We describe new developments for controlled fabrication of monodisperse non‐spherical particles using droplet microfluidics. The high degree of control afforded by microfluidic technologies enables generation of single and multiple emulsion droplets. We show that these droplets can be transformed to non‐spherical particles through further simple, spontaneous processing steps, including arrested coalescence, asymmetric polymer solidification, polymerization in microfluidic flow, and evaporation‐driven clustering. These versatile and scalable microfluidic approaches can be used for producing large quantities of non‐spherical particles that are monodisperse in both size and shape; these have great potential for commercial applications.