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Tailoring Polymeric Hydrogels through Cyclodextrin Host–Guest Complexation
Author(s) -
Guo Xuhong,
Wang Jie,
Li Li,
Pham DucTruc,
Clements Philip,
Lincoln Stephen F.,
May Bruce L.,
Chen Qingchuan,
Zheng Li,
Prud'homme Robert K.
Publication year - 2010
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200900560
Subject(s) - self healing hydrogels , steric effects , cyclodextrin , acrylate , polymer , intermolecular force , polymer chemistry , materials science , chemistry , polymer science , nanotechnology , chemical engineering , molecule , copolymer , organic chemistry , engineering
A close correllation between molecular‐level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β‐cyclodextrin (β‐CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host–guest complexation between β‐CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra‐ and intermolecular host–guest complexation are found to control poly(acrylate) isomeric inter‐strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials.