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Synthesis and Fluorescent Properties of Biodegradable Hyperbranched Poly(amido amine)s
Author(s) -
Yang Wen,
Pan CaiYuan
Publication year - 2009
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200900482
Subject(s) - fluorescence , amine gas treating , polymerization , piperazine , polymer , polymer chemistry , biocompatible material , chemistry , materials science , photochemistry , organic chemistry , medicine , physics , quantum mechanics , biomedical engineering
Disulfide‐functionalized hyperbranched poly(amido amine)s (HPAMAMs) were synthesized by Michael addition polymerization of N,N '‐cystaminebisacrylamide and 1‐(2‐aminoethyl)piperazine. The novel HPAMAMs displayed bright fluorescence, and the emissions bands cover nearly the whole visible wavelength range. When polymer solutions were excited at 330–385, 460–490, and 510–550 nm, blue, green, and red solutions were observed, respectively. The HPAMAMs are biodegradable and they can be easily cleaved by 2‐mercaptoethanol or glutathione, leading to a decrease in the fluorescence intensity. Studies of applications of the biocompatible and biodegradable HPAMAMs in fluorescence imaging technology and biological science are in progress.