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Polymersome/Silica Capsules by ‘Click’‐Chemistry
Author(s) -
Binder Wolfgang H.,
Sachsenhofer Robert
Publication year - 2008
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200800119
Subject(s) - polymersome , click chemistry , polymer chemistry , copolymer , cationic polymerization , telechelic polymer , ethylene oxide , micelle , cycloaddition , polymer , polymerization , chemistry , amphiphile , azide , materials science , end group , organic chemistry , aqueous solution , catalysis
Abstract Polyisobutylene/poly(ethylene oxide) diblock copolymers (PIB n ‐PEO m ) with variable block‐lengths ( n = 40, 75; m = 31, 52) have been prepared by a combination of living polymerization cationic methods and azide/alkyne ‘click’ chemistry. Allyl‐telechelic PIBs are transformed into the respective telechelic PIB‐azides (PIB‐N 3 ) by a quantitative procedure. Coupling of the PIB‐N 3 to acetylene‐telechelic PEO‐polymers is then quantitatively achieved by a Cu I ‐mediated cycloaddition reaction. The resulting diblock copolymers reveal lamellar structures in solution at concentrations up to 35 wt.‐%, whereas polymersomes are formed at lower concentrations. The resulting polymersomes can be silicified under inclusion of nanoparticles to generate micrometer‐sized, multifunctional capsules with a silica shell.