Premium
Novel pH‐ and Temperature‐Responsive Block Copolymers with Tunable pH‐Responsive Range
Author(s) -
He Chaoliang,
Zhao Changwen,
Chen Xuesi,
Guo Zhaojun,
Zhuang Xiuli,
Jing Xiabin
Publication year - 2008
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200700721
Subject(s) - copolymer , phase diagram , polymer chemistry , phase (matter) , materials science , transition temperature , atmospheric temperature range , chemical engineering , chemistry , polymer , thermodynamics , organic chemistry , physics , superconductivity , quantum mechanics , engineering , composite material
A series of novel pH‐ and temperature‐responsive diblock copolymers composed of poly( N ‐isopropylacrylamide) (PNIPAM) and poly[( L ‐glutamic acid)‐ co ‐( γ ‐benzyl L ‐glutamate)] [P(GA‐ co ‐BLG)] were prepared. The influence of hydrophobic benzyl groups on the phase transition of the copolymers was studied for the first time. With increasing BLG content in P(GA‐ co ‐BLG) block, the thermal phase transition of the diblock copolymer became sharper at a designated pH and the critical curve of phase diagram of the diblock copolymer shifted to a higher pH region. Notably, when the BLG content in P(GA‐ co ‐BLG) block was more than 30 mol.‐%, the diblock copolymer responded sharply to a narrow pH change in the region of pH 7.4–5.5.