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Macromolecular Recognition: Interaction of Cyclodextrins with an Alternating Copolymer of Sodium Maleate and Dodecyl Vinyl Ether
Author(s) -
Taura Daisuke,
Hashidzume Akihito,
Harada Akira
Publication year - 2007
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200700548
Subject(s) - micelle , copolymer , chemistry , aqueous solution , nuclear overhauser effect , ether , selectivity , vinyl ether , nuclear magnetic resonance spectroscopy , proton nmr , polymer chemistry , organic chemistry , polymer , catalysis
Interaction of cyclodextrins (CDs) with an alternating copolymer of sodium maleate and dodecyl vinyl ether (pC 12 MA), which forms micelle‐like aggregates in aqueous media, is investigated by several NMR techniques to explore the competition of the complexation of CDs with the dodecyl (C 12 ) groups and the self‐association of the C 12 groups. 1 H NMR and two‐dimensional nuclear Overhauser effect spectroscopy data demonstrate that α ‐CD interacts significantly with the C 12 groups in pC 12 MA but β ‐ or γ ‐CD does not, which indicates that the competition with self‐association of the C 12 groups enhances the selectivity towards α ‐CD. Furthermore, the binding isotherm prepared using 1 H NMR data exhibits a sigmoidal curve, which is indicative of cooperative complexation of α ‐CD with pC 12 MA.