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A Novel Approach to Magnetic Nanoadsorbents with High Binding Capacity for Bovine Serum Albumin
Author(s) -
Sun Yabin,
Ding Xiaobin,
Zheng Zhaohui,
Cheng Xu,
Hu Xinhua,
Peng Yuxing
Publication year - 2007
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200600727
Subject(s) - surface modification , bovine serum albumin , methacrylate , magnetic nanoparticles , nanoparticle , acrylic acid , polymerization , ionic strength , fourier transform infrared spectroscopy , materials science , chemical engineering , polymer , polymer chemistry , x ray photoelectron spectroscopy , chemistry , copolymer , nanotechnology , chromatography , organic chemistry , aqueous solution , engineering
Magnetic nanoadsorbents using Fe 3 O 4 nanoparticles as cores and poly(methyl acrylic acid) (PMAA) as ionic exchange groups were prepared through our novel approach. Two steps were involved in this approach: the first was to functionalize the magnetic nanoparticles (MNPs) with methacrylate double bonds via the combination of ligand exchange and condensation of methacryloxypropyltrimethoxysilane(MPS); the second was to graft PMAA chains onto the surface of MNPs through radical polymerization. The success of the various surface functionalization steps was ascertained using FTIR and XPS. The as‐synthesized PMAA‐coated MNPs were effective in binding bovine serum albumin (BSA) with a high capacity of 1 300 mg · g −1 .