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Nanofibrous Sugar Sticks Electrospun from Glycopolymers for Protein Separation via Molecular Recognition
Author(s) -
Yang Qian,
Wu Jian,
Li JunJie,
Hu MengXin,
Xu ZhiKang
Publication year - 2006
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200600470
Subject(s) - nanofiber , electrospinning , scanning electron microscope , sugar , materials science , acrylonitrile , adsorption , chemical engineering , polymer , polymer chemistry , chemistry , copolymer , composite material , organic chemistry , engineering
Summary: Nanofibrous sugar sticks with linear PANCGAMA and cyclic PANCAG glucose pendants were fabricated by electrospinning from acrylonitrile‐based glycopolymers. Field emission scanning electron microscope was used to characterize the morphologies of the nanofibers. Utilizing the specific carbohydrate‐protein interaction, these two kinds of nanofiber mats were applied to separate the protein mixtures. Con A and BSA were used as model proteins. The Con A/BSA mixture solution was isolated successfully by selective adsorption of Con A to the cyclic glucose pendants on the PANCAG nanofibrous sugar sticks. However, PANCGAMA nanofibers showed almost no selectivity for these two proteins due to the poor specificity between linear glucose pendants and Con A.Typical SEM images of nanofibers fabricated from PANCAG1.