Premium
Electrospun Nanofibers Modified with Phospholipid Moieties for Enzyme Immobilization
Author(s) -
Huang XiaoJun,
Xu ZhiKang,
Wan LingShu,
Innocent Christophe,
Seta Patrick
Publication year - 2006
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200600266
Subject(s) - nanofiber , phospholipid , lipase , materials science , chemical engineering , biocompatibility , electrospinning , immobilized enzyme , adsorption , polymer chemistry , organic chemistry , chemistry , membrane , nanotechnology , polymer , enzyme , composite material , biochemistry , engineering , metallurgy
Summary: PANCMPCs containing phospholipid side moieties were electrospun into nanofibers with a mean diameter of 90 nm. Field emission SEM was used to characterize the morphologies of the nanofibers. These phospholipid‐modified nanofibers were explored as supports for enzyme immobilization due to the characteristics of excellent biocompatibility, high surface/volume ratio, and porosity, which were beneficial to the catalytic efficiency and activity of immobilized enzymes. Lipase from Candida rugosa was immobilized on these nanofibers by adsorption. Preliminary results indicated that the properties of the immobilized lipase on these phospholipid‐modified nanofibers were greatly promising.Schematic representation of the structure and electrostatic properties of phospholipid‐modified nanofibers.