Premium
Unimolecular Amphiphilic Nanocontainers Based on Dendronized Linear Polymers
Author(s) -
Zhang ZhongBiao,
Teng YuHan,
Freas William,
Mohanty Dillip K.
Publication year - 2006
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200500843
Subject(s) - polyethylenimine , amphiphile , acrylate , polymer , dendrimer , macromolecule , polymer chemistry , alkyl , materials science , chemistry , chemical engineering , copolymer , organic chemistry , transfection , biochemistry , engineering , gene
Summary: Linear polymeric core, polyethylenimine (PEI), is successfully dendronized divergently using different‐generation polyamidoamine (PAMAM)‐type dendrons. The formed dendronized polymers are further end‐capped using long alkyl acrylate, hexyl acrylate, to give macromolecular amphiphiles, which perform as unimolecular nanocontainers, capable of encapsulating water‐soluble dye in their interiors. The encapsulation properties are found to be generation‐dependent, in which, at higher generations of nanocontainers, the cavity becomes more localized, due to dense packing of the dendrons at their termini.Dendronization of a linear polymeric core followed by capping with hydrophobic arms.