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Effect of Turbulent Flow on Coil‐Globule Transition of λ ‐DNA
Author(s) -
Lim Sung Taek,
Choi Hyoung Jin,
Chan ChiKeung
Publication year - 2005
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200500232
Subject(s) - spermidine , turbulence , dna , drag , transition (genetics) , chemistry , flow (mathematics) , chemical physics , materials science , biophysics , physics , mechanics , biochemistry , biology , gene , enzyme
Abstract Summary: The addition of spermidine (SPD) into turbulent flow as a condensing agent showed the abrupt change of turbulent drag reducing (DR) efficiency of λ ‐DNA in turbulent flow for the first time. The resultant asymptote DR efficiency explains the origin of those changes, which can be conclusively verified via the electrophoresis experiment. Despite the different fluid conditions, with and without condensing agent, all λ ‐DNA molecules possessed the same half‐cut dimension, implying that the discrete change of DNA conformation can dramatically alter the flow characteristics.Coil‐globule transition of DNA by spermidine.