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Statistical Megamer Morphologies and Materials from PAMAM Dendrimers
Author(s) -
Khopade Ajay J.,
Möhwald Helmuth
Publication year - 2005
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200400523
Subject(s) - dendrimer , transmission electron microscopy , amidoamine , poly(amidoamine) , chloroform , solvent , evaporation , materials science , pulmonary surfactant , chemical engineering , polymer chemistry , characterization (materials science) , chemistry , nanotechnology , organic chemistry , physics , engineering , thermodynamics
Summary: Generation‐4 poly(amidoamine) dendrimers (G4‐PAMAM) were cross‐linked using gluteraldehyde to obtain aldehyde‐activated G4‐PAMAM and cross‐linked G4‐PAMAM, termed pre‐megamers, which were grafted with octadecylamine (ODA) in chloroform (CHCl 3 ). Statistical megamer morphologies and particles were prepared by an emulsification solvent‐evaporation method using an ODA‐premegamer/CHCl 3 solution, surfactant, and water. Physicochemical characterization of the premegamers and megamers by various spectroscopic and microscopic techniques demonstrated their formation and properties useful in diagnostic and chromatographic applications.Formation of pre‐megamers and megamers and their transmission electron microscopy images.