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Real‐Time Scanning Force Microscopy of Macromolecular Conformational Transitions
Author(s) -
Gallyamov Marat O.,
Tartsch Bernd,
Khokhlov Alexei R.,
Sheiko Sergei S.,
Börner Hans G.,
Matyjaszewski Krzysztof,
Möller Martin
Publication year - 2004
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200400235
Subject(s) - mica , macromolecule , molecule , scanning force microscopy , chemistry , crystallography , microscopy , materials science , adsorption , nanotechnology , atomic force microscopy , optics , physics , composite material , organic chemistry , biochemistry
Summary: Comb‐like macromolecules were adsorbed on mica and imaged by scanning force microscopy in real time as they underwent a transition from an extended worm‐like conformation to globuli and vice versa. The conformational transition was effected by coadsorption of ethanol and water molecules. Coadsorption of the small molecules allowed manipulation of the adherence and spreading of the macromolecules, thus effecting the reptation like stretching and collapse of the single molecules.SFM images of three individual PMA‐g‐P n BuA brush molecules on mica 27 min (left, first collapse cycle) and 18 min (right, second collapse cycle) after injection of ethanol into the sample space.