Premium
Enzyme‐Catalyzed Preparation of Aliphatic Polyesters Containing Thioester Linkages
Author(s) -
Iwata Shin,
Toshima Kazunobu,
Matsumura Shuichi
Publication year - 2003
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200390070
Subject(s) - polyester , transesterification , candida antarctica , thioester , lipase , copolymer , catalysis , polymer chemistry , organic chemistry , chemistry , triacylglycerol lipase , enzyme , materials science , polymer
Aliphatic polyesters containing thioester linkages were enzymatically prepared by both the copolymerization of lactone with mercaptoalkanoic acid and by the transesterification of polyesters with mercaptoalkanoic acids. The enzymatic copolymerization of ε ‐caprolactone with 11‐mercaptoundecanoic acid (11MU) and 3‐mercaptopropionic acid (3MP) was performed under reduced pressure using an immobilized lipase from Candida antarctica (CA). The transesterification of poly( ε ‐caprolactone) and poly[( R )‐3‐hydroxybutyrate] was carried out with 11MU and 3MP using lipase CA under reduced pressure.