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An Electrochemical Robotic System for the Optimization of Amperometric Glucose Biosensors Based on a Library of Cathodic Electrodeposition Paints
Author(s) -
Reiter Sabine,
Ruhlig Dirk,
Ngounou Bertrand,
Neugebauer Sebastian,
Janiak Sandra,
Vilkanauskyte Aiste,
Erichsen Thomas,
Schuhmann Wolfgang
Publication year - 2004
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.200300207
Subject(s) - amperometry , biosensor , glucose oxidase , schematic , electrochemistry , materials science , electrode , cathodic protection , nanotechnology , polymer , chemistry , composite material , electronic engineering , engineering
Summary: A library of 148 cathodic electrodeposition paints was synthesized and the properties of related amperometric glucose biosensors were evaluated. For this a novel automatic electrochemical robotic system was designed. The automatic biosensor fabrication and characterization sequence involves the electrochemically induced precipitation of the cathodic paint on the electrode surface in the presence of glucose oxidase, the conditioning of the obtained polymer layer, the recording of a glucose calibration graph and the quantitative dissolution of the polymer film and cleaning of the electrode surface.Schematic representation of the developed electrochemical robotic system for electrochemical screening in microtiter plates.