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Synthesis of comb‐like polyurethanes containing hydrophilic phosphatidylcholine analogues in the main chains and hydrophobic long chain alkyl groups in the side chains
Author(s) -
Li YuJun,
Nakamura Naotoshi,
Chen TianMing,
Wang YanFeng,
Kitamura Masaya,
Nakaya Tadao
Publication year - 1996
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.1996.030171009
Subject(s) - amphiphile , side chain , alkyl , polymer chemistry , phospholipid , polyurethane , diol , phosphatidylcholine , hexamethylene diisocyanate , chemistry , moiety , organic chemistry , copolymer , polymer , membrane , biochemistry
Three new amphiphilic phospholipid diols containing hydrophilic phosphatidylcholine analogues in the main chains and hydrophobic octadecyl, hexadecyl or dodecyl alkyl groups in the side chains were synthesized. The typical phospholipid diol based on an octadecyl group was further reacted with diisocyanates such as hexamethylene diisocyanate (HDI), 2,4‐tolylene diisocyanate (TDI) and 4,4′‐methylenediphenyl diisocyanate (MDI), respectively. Preliminary studies suggest that polyurethane based on MDI shows a viscosity behavior similar to common polyelectrolytes and exhibits a therm decomposition peak at 244°C due to the phospholipid moiety and a melting point at 218°C.