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Enzymes in polymer chemistry, 9 . Polymerizable oligoesters from cholic acid via lipase catalyzed condensation reactions
Author(s) -
Noll Olaf,
Ritter Helmut
Publication year - 1996
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.1996.030170808
Subject(s) - lipase , cholic acid , catalysis , chemistry , condensation , polymer , enzyme , condensation polymer , organic chemistry , enzyme catalysis , polymer chemistry , condensation reaction , biochemistry , bile acid , physics , thermodynamics
Regioselective oligocondensation of cholic acid in the 3‐position was achieved in organic solution in the presence of a lipase from Candida antarctica . Furthermore, a mixture of cholic acid, 11‐methacryloylaminoundecanoic acid and the lipase resulted in the production of a radically polymerizable oligo(cholic acid ester) bearing exactly one methacrylic end group. This new monomer was polymerized radically yielding the corresponding comb‐polymers bearing several cholic acid esters at the end of the side chains.