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Hysteresis in the glucose permeability versus pH characteristic for a responsive hydrogel membrane
Author(s) -
Baker John P.,
Siegel Ronald A.
Publication year - 1996
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.1996.030170607
Subject(s) - permeability (electromagnetism) , permeation , membrane , methacrylic acid , hysteresis , chemistry , swelling , chemical engineering , polymer chemistry , semipermeable membrane , biophysics , materials science , chromatography , polymer , copolymer , composite material , organic chemistry , biochemistry , physics , quantum mechanics , engineering , biology
A side‐by‐side diffusion cell was used to study the permeability of glucose through a temperature‐ and pH‐sensitive poly( N ‐isopropylacrylamide‐ co ‐methacrylic acid) hydrogel membrane. At fixed temperature (37°C), lowering pH in one side of the cell induced hydrogel volume collapse and strongly attenuated glucose permeation across the membrane. Hysteresis was observed in the glucose permeability versus pH characteristic.