Temperature‐induced phase transition behaviors of random vs. graft copolymers of  N ‐isopropylacrylamide and acrylic acid | Zendy

Chen Guohua | Zendy; Hoffman Allan S. | Zendy

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Temperature‐induced phase transition behaviors of random vs. graft copolymers of N ‐isopropylacrylamide and acrylic acid

Author(s) -

Chen Guohua,

Hoffman Allan S.

Publication year - 1995

Publication title -

macromolecular rapid communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.348

H-Index - 154

eISSN - 1521-3927

pISSN - 1022-1336

DOI - 10.1002/marc.1995.030160304

Subject(s) - bioadhesive , poly(n isopropylacrylamide) , copolymer , acrylic acid , polymer chemistry , acrylic resin , lower critical solution temperature , phase transition , materials science , drug delivery , chemical engineering , chemistry , polymer , nanotechnology , composite material , thermodynamics , coating , physics , engineering

Graft copolymers of poly( N ‐isopropylacrylamide) (PNIPAAm) on a poly(acrylic acid) backbone retain the temperature‐induced phase transition behavior of PNIPAAm over a wide range of compositions even at pH 7,4 and should be useful for sustained‐release, bioadhesive drug delivery systems at physiologic conditions.

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