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Tannin‐Tethered Gelatin Hydrogels with Considerable Self‐Healing and Adhesive Performances
Author(s) -
Zhao Qiuxia,
Mu Shengdong,
Long Yanru,
Zhou Jin,
Chen Wuyong,
Astruc Didier,
Gaidau Carmen,
Gu Haibin
Publication year - 2019
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201800664
Subject(s) - self healing hydrogels , gelatin , materials science , adhesive , tannic acid , chemical engineering , covalent bond , biocompatible material , tissue engineering , genipin , self healing , nanotechnology , chitosan , polymer chemistry , composite material , biomedical engineering , layer (electronics) , organic chemistry , chemistry , medicine , alternative medicine , pathology , engineering
Hydrogels, especially the ones with self‐recovery and adhesive performances, have attracted more and more attention owing to their wide practical potential in the biomedical field involving cell delivery, wound filling, and tissue engineering. Tannic acid (TA), a nature‐derived gallol‐rich polyphenol, exhibits not only unique chelating properties with transition metal cations but also desirable anti‐oxidation properties and strong bonding capability to proteins and gelatin. Thus, taking advantage of the versatility of TA, a one‐pot method is proposed herein to produce TA‐modified gelatin hydrogels with the aid of NaIO 4 under basic conditions. By changing the amount of NaIO 4 used, the obtained hydrogels are covalently cross‐linked to different degrees and consequently exhibit diversity in their self‐healing and adhesive properties. The gelling time, viscoelasticity, and morphology of hydrogels are investigated, and when the feed molar ratio of NaIO 4 to TA is adjusted to 15:1, the fabricated hydrogel shows optimum self‐healing efficiency of 73% and adhesive strength of 36 kPa. Additionally, considering the completely natural origin of TA and gelatin, this study offers an original way for the fabrication of biocompatible self‐healing and adhesive materials.