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An Injectable Self‐Healing Multifluorescent Hydrogel Formed by Engineered Coiled‐Coil Polypeptide and Quantum Dots
Author(s) -
Yang Jie,
Zhao SunDuo,
Jin RuiMei,
Zhao DongHui,
Chen Wei,
Hu Wei,
Wang Qiong,
Liu Bo
Publication year - 2019
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201800658
Subject(s) - materials science , self healing hydrogels , quantum dot , self healing , nanotechnology , electromagnetic coil , self assembly , doping , polymer chemistry , optoelectronics , medicine , alternative medicine , engineering , pathology , electrical engineering
An injectable and self‐healing multifluorescent hydrogel system based on engineered coiled‐coil polypeptide and CdSe@ZnS quantum dots (QDs) is developed. The mechanical properties of the PC 10 A‐QD hydrogel are able to be tuned by changing the concentrations of PC 10 A and QDs. The G′ of PC 10 A hydrogel increases from 800 to 1000 Pa by doping 6 n m oil‐soluble CdSe@ZnS QDs. The PC 10 A‐QD hydrogel can easily pass through a 26‐gauge needle without clogging. In addition, through interfacial assembly of PC 10 A polypeptide on the surface of the PC 10 A‐QD hydrogel, each of these hydrogel can self‐assemble into a multifluorescent hydrogel. This approach for preparation of injectable self‐healing multifluorescent hydrogels is expected to apply in biomedicine.