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Poly(Lactic Acid) Fine Fibers Containing a Low Content of Superhydrophilic Multi‐Walled Carbon Nanotube Graphene Oxide Hybrid as Scaffolds for Biological Applications
Author(s) -
Andrade Patricia Oliveira,
Grinet Marco Antônio Vieira Macedo,
Costa Maira Maftoum,
Santo Ana Maria Espirito,
Marciano Fernanda Roberta,
Lobo Anderson Oliveira
Publication year - 2018
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201800317
Subject(s) - materials science , wetting , polylactic acid , graphene , crystallinity , carbon nanotube , oxide , superhydrophilicity , nanotube , chemical engineering , adhesion , composite material , fiber , nanotechnology , polymer , metallurgy , engineering
Herein, polylactic acid containing two different concentrations of superhydrophilic multiwalled carbon nanotube graphene oxide hybrid (MWCNT‐GO, 0.5 wt% and 5 wt%) is rotary‐jet spun. The morphological, thermal, and surface wettability properties are then evaluated. Biological properties, including cytotoxicity, fibroblast cell adhesion, and the overall bioactive effect, are also investigated. It is demonstrated that the thermal behavior is affected by the presence of MWCNT‐GO, as well as the crystallinity. The addition of MWCNT‐GO, even in small amounts, reduces the wettability property of the fibers, making them more hydrophobic. However, biological tests with these fibers show no cytotoxic effect in all fiber sample groups, even when MWCNT‐GO concentration is increased. Therefore, nano‐structured, porous, and biocompatible polymeric scaffolds are obtained, with a high surface area and with notable potential for tissue engineering applications.