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An Inexpensive, Portable Device for Point‐of‐Need Generation of Silver‐Nanoparticle Doped Cellulose Acetate Nanofibers for Advanced Wound Dressing
Author(s) -
Brako Francis,
Luo Chaojie,
Craig Duncan Q. M.,
Edirisinghe Mohan
Publication year - 2018
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201700586
Subject(s) - nanofiber , materials science , cellulose acetate , electrospinning , wound dressing , nanotechnology , cellulose , chemical engineering , composite material , polymer , engineering
This short communication describes the design and assembly of a new, miniaturized electrospinner to produce nanofibers at the site of need for drug delivery and wound dressing applications. The portable apparatus would eliminate the storage and transportation concerns with regards to the delicate nature of drug‐loaded nanofibers, thereby preserving product integrity at the site of use. Furthermore, the setup features a smaller size, a cheaper price, and components that are readily obtainable off‐the‐shelf, compared to those of available devices that are custom‐built and more expensive, making it desirable and accessible for other users in the field. As a proof‐of‐concept for wound care, the device is successfully used to electrospin three types of nanofibers comprised of pure cellulose acetate (CA), and CA respectively doped with 0.75 and 1.5 wt% silver nanoparticles. The miniaturized device is useful on account of the popularity of electrospinning as well as the potential to minimize wound infection due to the reduced manipulation of both the dressing and the wound from product generation to the point of need. Work is in progress to further develop the portable device and compare its product performance with traditional wound dressing materials for clinical translation.