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Polydopamine‐Assisted Electrochemical Fabrication of Polypyrrole Nanofibers on Bone Implants to Improve Bioactivity
Author(s) -
Wang Zhengao,
Zhou Lei,
Yu Peng,
Liu Yan,
Chen Junqi,
Liao Jingwen,
Li Weiping,
Chen Wei,
Zhou Wenhao,
Yi Xin,
Ouyang Kongyou,
Zhou Zhengnan,
Tan Guoxin,
Ning Chengyun
Publication year - 2016
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201600285
Subject(s) - polypyrrole , materials science , nanofiber , biomineralization , polymerization , nanotechnology , dopant , electrochemistry , monomer , conductive polymer , chemical engineering , polymer , composite material , doping , electrode , chemistry , optoelectronics , engineering
Dopamine is a molecule that facilitates biomineralization, and it is used to prepare electropolymerization‐induced polydopamine (PDA). For the first time, dopamine is used for template‐free electrochemical polymerization to form biocompatible polypyrrole (PPy) nanofiber coatings on bone implants. Dopamine monomers are electropolymerized to PDA chains affixed to biomedical titanium after the nanomicelles are tuned to self‐assemble by triggering the potential, resulting in nanofiber formation. Dopamine serves as a dopant to induce the formation of conductive PPy nanofibers and as a promoter to accelerate biomineralization, cell proliferation, and adhesion.