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Succinoglycan Octasaccharide Conjugated Polydiacetylene‐Doped Alginate Beads for Barium (II) Detection
Author(s) -
Yun Deokgyu,
Cho Eunae,
Dindulkar Someshwar D.,
Jung Seunho
Publication year - 2016
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201600060
Subject(s) - reductive amination , conjugated system , metal ions in aqueous solution , materials science , ligand (biochemistry) , fluorescence , sinorhizobium meliloti , vesicle , combinatorial chemistry , metal , nanotechnology , chemistry , biochemistry , polymer , catalysis , physics , quantum mechanics , membrane , mutant , gene , receptor , metallurgy , composite material
Detection methods for heavy metals are important and highly required due to their toxicity to the health of humans and the environment. Hence, using a polydiacetylene (PDA)‐based sensoring bead, the presence of barium ions is exclusively detected for the first time. The sensoring platform has been designed as a PDA vesicle functionalized with a succinoglycan octasaccharide subunit serving as a metal coordination ligand. First, the succinoglycan octasaccahride subunit is isolated from Sinorhizobium meliloti , successfully conjugated to pentacosa‐10,12‐diynoic acid via reductive amination, and the functionalized vesicle system is investigated for color and fluorescence changes targeting nine different metal ions. To further improve the long‐term storage stability and convenient handling of the vesicle detection system, the sensory vesicle is immobilized on millimeter‐sized alginate beads through the ionotropic gelation method. This study provides an opportunity to design and develop various carbohydrate‐based sensor materials.