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Macromol. Chem. Phys. 16/2018
Author(s) -
Moon Nicholas G.,
Mazzini Fiorella,
Pekkanen Allison M.,
Wilts Emily M.,
Long Timothy E.
Publication year - 2018
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201870038
Subject(s) - differential scanning calorimetry , polymer , polymer chemistry , materials science , monomer , glass transition , fourier transform infrared spectroscopy , dynamic mechanical analysis , polyurethane , comonomer , chemical engineering , composite material , physics , engineering , thermodynamics
Front Cover : In article 1800177 , Timothy E. Long and co‐workers report the characterization, and tissue scaffold applications of poly( β ‐thioester)s. The monomer isosorbide diacrylate (iSDA) and commercially available dithiols allow access to a range of biosourced, degradable polymers. Altering the dithiol identity significantly affects the glass transition Tgs of the polymer products; however, polymers do not exhibit Tgs above room temperature. Incorporating the comonomer N , N ′‐methylene bisacrylamide provides mechanical reinforcement through hydrogen bonding, resulting in soft, pliable materials. Differential scanning calorimetry (DSC) and variable temperature fourier‐transform infrared (FTIR) spectroscopy indicates that increases in mechanical integrity results from hydrogen bonding. Dynamic mechanical analysis (DMA) reveals materials that exhibit suitable moduli and service windows at body temperature. Biological evaluation demonstrates favorable cytotoxicity and cell attachment, rendering these materials potential candidates as novel scaffold materials for tissue growth.