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Backbone‐Based LCST‐Type Hyperbranched Poly(oligo(ethylene glycol)) with CO 2 ‐Reversible Iminoboronate Linkers
Author(s) -
Yu Jiabao,
Chao Huan,
Li Guo,
Tang Rupei,
Liu Zhaotie,
Liu Zhongwen,
Jiang Jinqiang
Publication year - 2018
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201800346
Subject(s) - lower critical solution temperature , ethylene glycol , polymer chemistry , protonation , aqueous solution , polymer , chemistry , hydrolysis , organic chemistry , copolymer , ion
Due to the very weak acidity of CO 2 in water, the trigger of CO 2 is always used to tune the physico‐chemical properties of polymeric materials through the protonation of organic bases rather than the hydrolysis of acid‐labile moieties contained in polymeric structures. Herein, a novel strategy of gas‐switchable lower critical solution temperature (LCST)‐type hyperbranched polymer of iminoboronate‐linked hyperbranched poly(oligo‐(ethylene glycol)) (IB‐hPOEG), by employing CO 2 ‐acidolyzable iminoboronates as linkers and protonable tertiary amines as branch points, is presented. Upon alternative CO 2 and N 2 , iminoboronates are partially reversibly hydrolyzed and tertiary amines are repeatedly protonated. This leads to a tunable thermo‐responsive behavior of IB‐hPOEG aqueous solution with a broad range of T cp at 28–78 °C intervals by varying the molar ratio of boronic acid, polymer concentration, or bubbling of CO 2 and N 2 . This gas‐controllable LCST‐type hyperbranched polymer with CO 2 ‐hydrolyzable iminoboronates is believed to have a promising potential for advanced biomedical and material applications such as drug delivery, gene transfection, functional coatings, etc.