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Functional Surfaces Constructed with Hyperbranched Copolymers as Optical Imaging and Electrochemical Cell Sensing Platforms
Author(s) -
Balta Sebila,
Aydogan Cansu,
Demir Bilal,
Geyik Caner,
Ciftci Mustafa,
Guler Emine,
Odaci Demirkol Dilek,
Timur Suna,
Yagci Yusuf
Publication year - 2018
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201700433
Subject(s) - methacrylate , cyclic voltammetry , materials science , copolymer , methyl methacrylate , polymer chemistry , polymerization , electrochemistry , polymer , branching (polymer chemistry) , conductive polymer , chemical engineering , chemistry , electrode , composite material , engineering
Abstract In the present study, hyperbranched copolymers (HBCs), namely poly(methyl methacrylate) (PMMA)‐ co ‐poly(2‐hydroxyethylmethacrylate) and PMMA‐ co ‐poly(2‐dimethylamino ethyl methacrylate), are photochemically synthesized by self‐condensing vinyl polymerization of methyl methacrylate with the corresponding inimer using Type II photoinitiators. HBCs with different functional group and branching densities are used as surface coating materials in cellular adhesion and the respective electrochemical‐based studies. After the main surface characterization of the synthesized three HBCs with contact angle measurements and atomic force microscopy, HaCaT keratinocytes and human neuroglioblastoma (U‐87MG) cell lines to the surfaces are conducted. The adherence of cells is proven by both fluorescence cell imaging and electrochemical methods such as cyclic voltammetry and differential pulse voltammetry. The described strategy involving hyperbranched polymers offers great potential for fabricating various new surfaces in particular “on‐chip‐sensing” applications.