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Fluorescent ROMP Monomers and Copolymers for Biomedical Applications
Author(s) -
Riga Esther K.,
Boschert David,
Vöhringer Maria,
Widyaya Vania Tanda,
Kurowska Monika,
Hartleb Wibke,
Lienkamp Karen
Publication year - 2017
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201700273
Subject(s) - romp , monomer , polymer chemistry , copolymer , metathesis , polymerization , chemistry , fluorescence , gel permeation chromatography , ring opening metathesis polymerisation , polymer , organic chemistry , physics , quantum mechanics
The synthesis and characterization of a series of green‐, blue‐, and red‐fluorescent exo ‐oxanorbornene acid and imide monomers carrying nitrobenzofurazan, coumarin, and rhodamin B, respectively, as fluorophores are presented. These monomers carry oxanorbornene as polymerizable unit, and are readily copolymerized with bioactive functional oxanorbornene monomers by ring‐opening metathesis polymerization, as demonstrated by gel permeation chromatography and NMR spectroscopy. Due to the ease of synthesis of these monomers, and their cost‐effectiveness compared many to other fluorescent probes, they are useful for biomaterial applications.