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Microfluidic Studies of Polymer Adsorption in Flow
Author(s) -
Salari Alinaghi,
Kumacheva Eugenia
Publication year - 2017
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201600328
Subject(s) - microchannel , microfluidics , polymer , biofouling , nanotechnology , adsorption , materials science , flow (mathematics) , chemistry , organic chemistry , composite material , mechanics , biochemistry , physics , membrane
Adsorption of polymer molecules under flow conditions governs a broad range of desired or undesired phenomena and has a broad range of applications. Microfluidic platforms integrated with analytical instrumentation offer the capability to study polymer adsorption in flow in a time‐ and labour‐efficient manner. Precise control of the microchannel dimensions and flow parameters enables accurate control of shear forces imposed on polymer solutions and on the molecules deposited on the surface, along with high sensitivity, enhanced reliability, and low reagent consumption. This review highlights recent advances in theoretical and experimental microfluidic studies of polymer immobilization under flow conditions in three area, namely, biosensing, biofouling, and studies of thrombosis and hemostasis.