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An Alternating Copolymer of a Tetrapeptide and a Tetrathiophene Prepared by a Click Reaction: A Study of the Synthesis and Assembly Behavior
Author(s) -
Gong Ruiying,
Guo Zongxia,
Li Fei,
Song Yubao,
Mu Youbing,
Li Ming,
Wan Xiaobo
Publication year - 2014
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201300563
Subject(s) - copolymer , tetrapeptide , self assembly , oligopeptide , polymer chemistry , click chemistry , chemistry , materials science , stereochemistry , peptide , organic chemistry , polymer , biochemistry
Alternating copolymers of an oligopeptide (N 3 ‐GVGV‐N 3 , where G: glycine; V: valine) and an oligothiophene (5,5′‐bis(ethynyl)‐3,3'‐dioctyltetrathiophene) are prepared by click chemistry. The experimental results discover that these copolymers exhibit strong molecular‐weight‐dependent self‐assembly behaviors. The copolymer P1 with the lowest weight‐average molecular weight (M ¯ w= 7400 g mol −1 ), assembles into well‐ordered fibrous nanostructures. P3 (M ¯ w= 16 980 g mol −1 ) assembles into nanoballs. P2, which has the mediumM ¯ wbetween P1 and P3, (M ¯ w= 14 800 g mol −1 ), exhibits more‐complicated self‐assembly behaviors, more like a transition state between the other two. All of the results suggest the self‐assembly ability of these oligopeptide segments might be the major reason for the nano‐structure evolution.