Premium
Core‐Shell Structures of Oligosaccharide‐Functionalized Hyperbranched Poly(ethylene imines)
Author(s) -
Thünemann Andreas F.,
Bienert Ralf,
Appelhans Dietmar,
Voit Brigitte
Publication year - 2012
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201100490
Subject(s) - small angle x ray scattering , polymer chemistry , scattering , materials science , dynamic light scattering , copolymer , chemistry , polymer , chemical engineering , nanoparticle , nanotechnology , physics , optics , engineering , composite material
Hyperbranched poly(ethylene imine)s (PEIs) functionalized with maltose, maltotriose, and maltoheptaose form distinct core‐shell globular nanoparticles as revealed by small‐angle X‐ray scattering (SAXS). The solution structures are quantified using the Beaucage unified exponential/power‐law approach. SAXS results were confirmed with dynamic light scattering (DLS). We found that all PEI structures are completely insensitive to changes of temperature (5 °C < T < 80 °C) and pH (1 < pH < 10). This remarkable stability of a compact spherical polymeric structure makes the modified PEIs promising for a wide range of biomedical applications.