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Amphiphilic PEG ‐b‐ PMCL ‐b‐ PDMAEMA Triblock Copolymers: From Synthesis to Physico‐Chemistry of Self‐Assembled Structures
Author(s) -
Matter Yves,
Enea Ramona,
Casse Olivier,
Lee Cameron C.,
Baryza Jeremy,
Meier Wolfgang
Publication year - 2011
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201000661
Subject(s) - copolymer , dispersity , amphiphile , polymer , polymer chemistry , self assembly , nanoparticle , materials science , dynamic light scattering , solvent , chemical engineering , chemistry , nanotechnology , organic chemistry , engineering , composite material
A synthetic route toward a new family of amphiphilic mPEG ‐b‐ PMCL ‐b‐ PDMAEMA triblock copolymers is reported. Chemical structures and compositions are confirmed by 1 H NMR and SEC. Polydispersity indices are typically <1.4, indicating good control of the reactions. The physicochemical parameters associated with mPEG ‐b‐ PMCL ‐b‐ PDMAEMA self‐assembled structures are investigated. Nanoparticles are prepared via a co‐solvent method, and parameters such as nanoparticle $\overline {M} _{{\rm w}} $ , N agg , A 2 , and R h are calculated based on static and dynamic light scattering data. Critical aggregation concentrations for the polymers are determined by measuring surface tensions of polymer solutions. TEM is employed to visualize the morphology of the assemblies.