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“Click Chemistry” as a Facile Approach to the Synthesis of Polyphosphazene Glycopolymers
Author(s) -
Huang Xu,
Huang XiaoJun,
Yu AnGuo,
Wang Cang,
Dai ZhengWei,
Xu ZhiKang
Publication year - 2011
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201000439
Subject(s) - polyphosphazene , phosphazene , click chemistry , azide , alkyne , chemistry , nucleophilic substitution , substituent , polymer chemistry , combinatorial chemistry , organic chemistry , polymer , catalysis
A versatile approach based on click chemistry to synthesize polyphosphazene glycopolymers is presented. The glucose‐substituted polyphosphazene was synthesized by nucleophilic substitution of poly(dichlorophosphazene) with propargylamine and the subsequent azide/alkyne “click” reaction of poly[di(propargylamine)phosphazene] (PDPAP) with azidosugar. The relative proportion of the glucose substituent can be easily controlled over a broad range by varying the amount of azidoglucose used in the azide/alkyne “click” reaction.