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Poly( ε ‐caprolactone)‐ graft ‐poly(2‐(dimethylamino)ethyl methacrylate) Amphiphilic Copolymers Prepared via a Combination of ROP and ATRP: Synthesis, Characterization, and Self‐Assembly Behavior
Author(s) -
Guo Shutao,
Wang Weiwei,
Deng Liandong,
Xing Jinfeng,
Dong Anjie
Publication year - 2010
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.201000103
Subject(s) - copolymer , polymer chemistry , methacrylate , amphiphile , caprolactone , polymer , materials science , nanoparticle , fourier transform infrared spectroscopy , chemical engineering , nanotechnology , composite material , engineering
Poly( ε ‐caprolactone)‐ graft ‐poly(2‐(dimethylamino) ethyl methacrylate) (PCL‐ g ‐PDMAEMAs), a kind of amphiphilic graft copolymer, was prepared by combination of ROP and ATRP. The FTIR, 1 H NMR, and GPC results indicate that well‐defined polymers with controlled graft density and length of side chain were successfully synthesized. We prepared PCL‐ g ‐PDMAEMA nanoparticles by employing a nanoprecipitation technique. The pH‐ and thermosensitive properties of PCL‐ g ‐PDMAEMA nanoparticles were investigated by 1 H NMR, TEM, and DLS. It was found that the nanoparticles with an average size of 120 nm presented core–shell structure in aqueous dispersion. Furthermore, the nanoparticles are sensitive to temperature in base while not in an acidic environment.