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Synthesis and Electro‐Optical Properties of a Novel DNA–Lipid Complex Carrying Carbazole Moieties
Author(s) -
Qu Jinqing,
Liu Lujing,
Chen Huanqin,
Ogata Naoya,
Masuda Toshio
Publication year - 2010
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.200900397
Subject(s) - carbazole , chemistry , cationic polymerization , dna , methanol , toluene , quantum yield , lipid bilayer , fluorescence , organic chemistry , photochemistry , membrane , biochemistry , physics , quantum mechanics
A novel DNA–lipid complex carrying carbazole (Cz) moieties was prepared by substituting the sodium counter cation with cationic lipid, namely lipid(2Cz), in which the actual mole ratio of phosphate to lipid was 1:1.05. The DNA–lipid(2Cz) complex was soluble in common organic solvents including CHCl 3 , CH 2 Cl 2 , methanol, and ethanol, while insoluble in THF, toluene, and water. CD spectroscopy revealed that the DNA–lipid complex took a predominantly double helical structure in methanol and that the helical structure was fairly stable against heating. A solution of the DNA–lipid(2Cz) complex emitted fluorescence in 40.0% quantum yield, which was lower than that of the corresponding lipid(2Cz) (76%). The cyclic voltammograms of the complex indicated that the oxidation potential of DNA–lipid(2Cz) was 0.65 V. The onset temperature of weight loss of the DNA–lipid complex is 230 °C according to TGA in air.