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Double‐Hydrophilic and Amphiphilic Block Copolymers Synthesized by RAFT Polymerization of Monomers Carrying Chiral Amino Acids
Author(s) -
Mori Hideharu,
Matsuyama Motonobu,
Endo Takeshi
Publication year - 2009
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.200800446
Subject(s) - copolymer , amphiphile , polymer chemistry , raft , reversible addition−fragmentation chain transfer polymerization , polymerization , monomer , chain transfer , chemistry , chirality (physics) , living polymerization , radical polymerization , polymer , organic chemistry , chiral symmetry breaking , physics , quantum mechanics , nambu–jona lasinio model , quark
Double‐hydrophilic and amphiphilic block copolymers with characteristic chiroptical properties ( L ‐ L and L ‐ D types) were synthesized by RAFT polymerization. Five N ‐acryloylamino acids with different hydrophilicity and chirality were employed, which included A‐( L )Phe‐OMe, A‐( L )Phe‐OH, A‐( L )Ala‐OH, and their D ‐forms [A‐( D )Phe‐OH and A‐( D )Ala‐OH], respectively. The RAFT polymerization of the unprotected monomer using the hydrophobic and hydrophilic macro‐chain transfer agents provided well‐defined block copolymers. Chiroptical properties and assembled structures were evaluated by CD, UV‐vis and DLS measurements.