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Monolithic Media Prepared Via Electron Beam Curing for Proteins Separation and Flow‐Through Catalysis
Author(s) -
Bandari Rajendar,
Knolle Wolfgang,
PragerDuschke Andrea,
Gläsel HansJürgen,
Buchmeiser Michael R.
Publication year - 2007
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.200600646
Subject(s) - monolith , copolymer , polymerization , materials science , monomer , polymer chemistry , styrene , surface modification , methacrylate , acrylate , chemical engineering , monolithic hplc column , catalysis , chemistry , polymer , composite material , organic chemistry , capillary action , engineering
A novel approach to acrylate/methacrylate‐based monolithic systems via electron‐beam (EB) initiated polymerization is described. The thus obtained monolithic columns were found suitable for the analytical scale separation of proteins. The novel concept of monolith synthesis was successfully extended to the synthesis of large diameter (20 mm × 300 mm id) monolithic columns applying EB irradiation in a pulsed mode. A homogeneous structure in terms of particle size and porous structure was again realized throughout the entire monolith. Functionalization of the monolithic columns was accomplished via copolymerization of a functional monomer, N,N ‐dipyrid‐2‐ylmethacryl amide. The thus obtained functional monoliths were loaded with Pd (II) and used for the Heck‐coupling of styrene with iodobenzene in a continuous process.