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Pyrene End‐Labeled Diblock Glycopolymers: Synthesis and Aggregation
Author(s) -
Lu FengZhu,
Meng JianQiang,
Du FuSheng,
Li ZiChen,
Zhang BaoYan
Publication year - 2005
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.200400354
Subject(s) - copolymer , glycopolymer , amphiphile , pyrene , polymer chemistry , chemistry , glutaraldehyde , dimethylformamide , caprolactone , solvent , polymer , organic chemistry
Summary: A pyrene end‐labeled amphiphilic block copolymer, poly( ε ‐caprolactone)‐ block ‐poly[6‐ O ‐(4‐vinylbenzyl)‐ D ‐galactose] (Py‐PCL‐ b ‐PVBG), was synthesized by a four‐step method. The aggregation behavior of the diblock copolymer in solution was studied by monitoring the fluorescence of pyrene. TEM measurements revealed that the aggregates obtained by first dissolving the copolymer in N , N ‐dimethylformamide (DMF), followed by the addition of water, were primarily spheres with the PCL blocks in the core. The PVBG corona was then crosslinked with glutaraldehyde. Final removal of the PCL core was accomplished by degradation under basic conditions, which resulted in the formation of hollow glycopolymer nanospheres.Structure of poly( ε ‐caprolactone)‐ block ‐poly[6‐ O ‐(4‐vinylbenzyl)‐ D ‐galactose].