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Physico‐chemical properties of hyaluronan and its hydrophobic derivatives: a calorimetric and viscometric study
Author(s) -
Geciova Renata,
Flaibani Antonella,
Delben Franco,
Liut Gianfranco,
Urbani Ranieri,
Cesáro Attilio
Publication year - 1995
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/macp.1995.021960914
Subject(s) - polyelectrolyte , counterion condensation , counterion , chemistry , aqueous solution , dilution , ionic strength , viscosity , polymer chemistry , intrinsic viscosity , ionic bonding , thermodynamics , polymer , organic chemistry , ion , physics
The physico‐chemical properties of a series of hyaluronan derivatives were studied with the aim of exploring some aspects of the role of electrostatic interactions on the aggregation of these chains in aqueous solution. Experimental data were obtained from calorimetric measurements of the dilution process in water. The data were analysed in terms of the structural charge parameter, ζ, with the polyelectrolyte counterion condensation theory. In addition, intrinsic viscosity data of the hyaluronan derivatives were obtained at several different values of the ionic strength and discussed on the basis of the effect of charge density change upon the elongation properties of the polyelectrolyte chains.