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Effect of human albumin on corrosion and biological behavior of CoCrMo
Author(s) -
Ionita D.,
Golgovici F.,
Demetrescu I.,
Sajin M.,
PandeleaDobrovicescu G.R.
Publication year - 2017
Publication title -
materials and corrosion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.487
H-Index - 55
eISSN - 1521-4176
pISSN - 0947-5117
DOI - 10.1002/maco.201609406
Subject(s) - dielectric spectroscopy , corrosion , albumin , alloy , electrochemistry , materials science , adsorption , polarization (electrochemistry) , human serum albumin , metallurgy , chemistry , chemical engineering , nuclear chemistry , chromatography , biochemistry , organic chemistry , electrode , engineering
The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy The electrochemical behavior of the alloy was tested in SBF with and without HSA. The used electrochemical methods have been open circuit potential measurement, potentiodynamic polarization, and electrochemical impedance spectroscopy. Albumin adsorption has been evaluated spectrophotometrically using both FT–IR and UV–VIS investigation methods. The human albumin acts as an inhibitor of corrosion reducing corrosion current until five time. The mechanism of inhibition is due to a protective barrier based on a complex metal‐protein formation and evidenced by impedance spectroscopy procedure. Biological tests confirmed non hemocompatibility of CoCrMo alloy and a non trombogenic behavior. No blood cell shape modification was observed as well.