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Application of Zwitterionic Polymer Hydrogels to Optical Tissue Clearing for 3D Fluorescence Imaging
Author(s) -
Kojima Chie,
Koda Takayuki,
Nariai Tetsuro,
Ichihara Junji,
Sugiura Kikuya,
Matsumoto Akikazu
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202170024
Subject(s) - self healing hydrogels , fluorescence , polymer , fluorescence lifetime imaging microscopy , optical imaging , clearing , chemistry , biophysics , materials science , nanotechnology , biomedical engineering , polymer chemistry , optics , organic chemistry , medicine , physics , finance , economics , biology
Front Cover : This picture shows the optical clearing process of a brain tissue to visualize the 3D vascular network in fluorescence imaging. Zwitterionic polymer hydrogels promoted the optical tissue clearing process by discharging lipid molecules. Phospholipid‐mimetic polymer hydrogels are the most useful for the optical tissue clearing as well as the 3D fluorescence imaging. This is reported by Chie Kojima and co‐workers in article number 2100170.