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Polymer–Protein Hybrid Network Involving Mucin: A Mineralized Biomimetic Template for Bone Tissue Engineering
Author(s) -
Barik Debyashreeta,
Bejugam Pruthvi Raj,
Nayak Chumki,
Mohanty Khirabdhi Tanaya,
Singha Achintya,
Declercq Heidi A.,
Dash Mamoni
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202170016
Subject(s) - mucin , scaffold , chemistry , tissue engineering , protein engineering , in silico , microbiology and biotechnology , biochemistry , biomedical engineering , biology , engineering , gene , enzyme
Back Cover : Mucins are a diverse family of densely glycosylated proteins with a potential role in the dynamic bone formation and remodeling process. The in silico protein–protein interaction analysis of collagen–mucin predicts that these proteins have a sufficient affinity towards each other, leading to a suitable chemical strategy for development as a polymer–protein hybrid scaffold. The scaffolds exhibit porosity and promote cell viability and proliferation opening new possible applications for bone tissue engineering. This is reported by Mamoni Dash and co‐workers in article number 2000381.