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Miktoarm Star Polymers with Environment‐Selective ROS/GSH Responsive Locations: From Modular Synthesis to Tuned Drug Release through Micellar Partial Corona Shedding and/or Core Disassembly
Author(s) -
Lotocki Victor,
Yazdani Hossein,
Zhang Qiaochu,
Gran Evan Rizzel,
Nyrko Anastasiia,
Maysinger Dusica,
Kakkar Ashok
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202170005
Subject(s) - nanocarriers , corona (planetary geology) , polymer , modular design , chemistry , nanotechnology , drug delivery , materials science , computer science , organic chemistry , physics , astrobiology , venus , operating system
Back Cover : Miktoarm polymers are developed using modular synthesis with environment selective functional groups judiciously placed in the star structure. Drug release from their aqueous assemblies is controlled through partial corona shedding upon interaction with ROS extracellularly, and complete nanocarrier disassembly intracellularly with GSH. This is reported by Victor Lotocki, Hossein Yazdani, Qiaochu Zhang, Evan Rizzel Gran, Anastasiia Nyrko, Dusica Maysinger, Ashok Kakkar in article number 2000305.