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Polymeric Nanoreactors as Emerging Nanoplatforms for Cancer Precise Nanomedicine
Author(s) -
Li Xin,
Zhao Xiaopeng,
Lv Runkai,
Hao Linhui,
Huo Fengwei,
Yao Xikuang
Publication year - 2021
Publication title -
macromolecular bioscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 105
eISSN - 1616-5195
pISSN - 1616-5187
DOI - 10.1002/mabi.202000424
Subject(s) - nanoreactor , nanomedicine , nanotechnology , cancer therapy , materials science , nanoparticle , cancer , medicine
How to precisely detect and effectively cure cancer which is defined as precise nanomedicine has drawn great attention worldwide. Polymeric nanoreactors which can in situ catalyze inert species into activated ones, can greatly increase imaging quality and enhance therapeutic effects along with decreased background interference and reduced serious side effects. After a brief introduction, the design and preparation of polymeric nanoreactors are discussed from the following aspects, that is, solvent‐switch, pH‐tuning, film rehydration, hard template, electrostatic interaction, and polymerization‐induced self‐assembly (PISA). Subsequently, the biomedical applications of these nanoreactors in the fields of cancer imaging, cancer therapy, and cancer theranostics are highlighted. The last but not least, conclusions and future perspectives about polymeric nanoreactors are given. It is believed that polymeric nanoreactors can bring a great opportunity for future fabrication and clinical translation of precise nanomedicine.